[Opt-net] DOTcvpSB, a Matlab toolbox for dynamic optimization in systems biology

Julio R. Banga julio at iim.csic.es
Tue Sep 15 13:03:14 MEST 2009


We are pleased to announce DOTcvpSB, a Matlab toolbox
for dynamic optimization of nonlinear dynamic systems,
focused on applications in systems biology.

Software and documentation are available at:
http://www.iim.csic.es/~dotcvpsb/

DOTcvpSB facilitates the statement and solution of
dyamic optimization (optimal control) problems related
with biological systems, modelled with ODEs (although
arbitrary black-box models can be handled as well).
The toolbox can import SBML models for the dynamics via
the SBMLtoolbox.

Examples of problems provided with the toolbox:
- optimal drug infusion to a patient
- minimization of intracellular oscillations
- bioreactor optimization

DOTcvpSB is described in the following paper:

Hirmajer, T., E. Balsa-Canto and J. R. Banga (2009)
DOTcvpSB, a software toolbox for dynamic optimization
in systems biology. BMC Bioinformatics 2009, 10:199.
http://www.biomedcentral.com/1471-2105/10/199/abstract/


More details, documentation and examples available at:
http://www.iim.csic.es/~dotcvpsb/

Regards,

Julio R. Banga ( julio at iim.csic.es )

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